Regulation of the Gene for Estrogenic 17-Ketosteroid Reductase Lying on Chromosome 17cen→q25
نویسندگان
چکیده
منابع مشابه
Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen----q25.
17-Ketosteroid reductase (17KSR), also known as 17 beta-hydroxysteroid dehydrogenase, catalyzes the reversible interconversion of estradiol to estrone and of androstenedione to testosterone. Using a recently cloned human placental 17KSR cDNA, we show that the 1.4-kilobase mRNA for this enzyme is detected only in tissues producing estrogens, and a 2.4-kilobase mRNA is detected in some estrogenic...
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15 صفحه اولA method for the quantitative analysis of 17-ketosteroid mixtures.
Neher and Wettstein (1) have recently published the details of a paper chromatographic method for the separation of weakly polar steroids, with a heptane-phenyl Cellosolve solvent system. Savard (2) has described the separation of 17-ketosteroids on paper with ligroin as the mobile phase and propylene glycol as the stationary phase. Starting from the basic work of these authors, a method has be...
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The rat beige (bg) autosomal recessive gene, causing Chediak-Higashi Syndrome (CHS) in rat, was mapped on Chr 17 by using synteny of rat to mouse and humans. The linkage between the beige gene and PCR-amplified microsatellite markers in (DA-bg x BN)F1 x DA-bg backcross progeny was analysed. The recombination frequency was 9.5% between Prl and Acrm and 19.1% between Acrm and bg. The proposed ord...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1989
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)47083-x